Flupyradifurone (PC Code 122304, 2(5H-(furanone), 4-{{(6-chloro-3-pyridinyl)methyl](2,2-difluoroethyl)amino]-, also known as BYI 02960) is a new active ingredient proposed for use as a systemic insecticide. The chemical belongs to the butenolide class of insecticides and the insecticidal activity of flupyradifurone is similar to the neonicotinoids with agonist activity in nicotinic acetylcholine receptors, making it a member of the Insecticide Resistance Action Committee (IRAC) Group 4 insecticide class. The environmental fate assessment indicates that depending on soil conditions and weather, flupyradifurone may persist in soil and it may be transported through a range of dissipation routes (i.e., runoff, erosion, leaching) to surface or groundwater, where the compound may also persist. Given the uses of flupyradifurone and its environmental fate properties, there is a likelihood of exposure to non-target terrestrial and/or aquatic organisms. Flupyradifurone may be transported to surface water and groundwater via runoff, leaching, and spray drift. It may be transported to offsite terrestrial environments via spray drift. When used in accordance with the label, flupyradifurone may result in potential adverse effects upon the survival, growth, and reproduction of non-target terrestrial and aquatic organisms. Based on the reduced risk assessment (USEPA, 2013, D408685), there will be potential direct risks to aquatic invertebrates and birds. On an acute exposure basis, flupyradifurone ranges from being slightly toxic to very highly toxic to aquatic invertebrates depending on the species tested. Based on the most sensitive species, the primary risks of concern in this assessment are for freshwater and estuarine/marine invertebrates inhabiting both the water column and benthic environments.
Source:
U.S. EPA. Environmental Fate and Ecological Risk Assessment for Foliar, Soil Drench, and Seed Treatment Uses of the New Insecticide Flupyradifurone (BYI 02960), Memorandum dated June 25, 2014
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