According to a hypothesis proposed by the U.S. Geological Survey and collaborators at National Institutes of Health, bats recovering from white-nose syndrome show evidence of immune reconstitution inflammatory syndrome (IRIS), a condition that was first described in HIV-AIDS patients. IRIS is a syndrome in which an organism's immune system, which has been suppressed, reactivates and, perceiving a serious infection around it, goes into overdrive resulting in severe inflammation and tissue damage in infected areas. In both human patients with HIV-AIDS and bats with WNS, the functioning of the immune system is severely reduced. For humans, this occurs when the HIV virus attacks the patient's white blood cells. In bats, this occurs during normal hibernation. IRIS can be fatal to both humans and bats.
"The potential discovery of IRIS in bats infected with white-nose syndrome is incredibly significant in terms of understanding both the reasons for bat mortality and basic immune response," said USGS Director Marcia McNutt. "This discovery could also prove significant for studies on treatment for AIDS."
Source: Environmental Protection, 26 November 2012
http://eponline.com/articles/2012/11/26/similarities-found-in-white-nos…
- Login om te reageren