On December 28, 2015, the U.S. Environmental Protection Agency (EPA) finalized important changes to the “minimum risk” pesticide exemption under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). See EPA, “Pesticides; Revisions to Minimum Risk Exemption,” 80 Fed. Reg. 80653 (Dec. 28, 2015). EPA’s new rule goes into effect February 26, 2016, with the exception of the deadline for compliance with new labeling requirements for minimum risk products, which is February 26, 2019. EPA’s action follows changes proposed in December 2012 and marks the first set of revisions to EPA’s minimum risk pesticide regulations since the Agency originally promulgated them in 1996. As briefly summarized below, the changes include more detailed EPA listings of the active and inert ingredients that may be used in minimum risk pesticides. Although EPA has not added or subtracted any ingredients from its lists of eligible minimum risk product ingredients, in its survey of personal insect repellent products currently distributed as minimum risk pesticides, it found that nearly half contain ingredients not permitted by its regulations. Based on this analysis, EPA suggests that the more detailed listings included in its newly codified provisions may require manufacturers who currently distribute pesticides under the minimum risk exemption to reformulate their products to achieve compliance.